30^th World Psychiatrists and Psychologists Meet October 01-02, 2018 Osaka, Japan

Gernot Kriegshauser has completed his PhD in Biochemistry from University of Vienna and his MD from Medical University of Vienna and is currently specializing in Clinical Chemistry and Laboratory Medicine at the General Hospital Steyr. He has a strong track record in R&D from ViennaLab Diagnostics GmbH before he started his studies to become a general practitioner. He has published more than 40 papers in reputed journals and has been serving as a Technical Consultant in Molecular Diagnostics for over 10 years.

Statement of the Problem: So far, studies on the association of serum lipid levels and depressive disorder are contradictory. Therefore, the objective of the this study was to investigate possible associations between serum lipid alterations in a large sample of well-characterized patients including men and women over a broad age range sub-grouped by the presence or absence of major depression. Methodology & Theoretical Orientation: A total of 246 participants aged between 18-70 years were recruited of whom 94 suffered from major depressive without any other psychiatric comorbidity. A total of 152 individuals with neither a depressive symptomatology nor a former history of psychiatric disorder served as healthy controls. All study participants filled out the Beck Depression Inventory (BDI-II) questionnaire and were investigated for their complete lipid status (i.e.,triglycerides, total cholesterol, LDL/HDL-cholesterol). Findings: 94 patients with major depression showed significantly higher median (interquartile range) serum triglyceride levels (108.0 [75.8-154.1] vs. 84.0 [63.0-132.2] mg/dL, p=0.014) and significantly lower HDL-cholesterol levels (55.0 [46.9-123.0] vs. 61.5 [47.4-72.6] mg/dL, p=0.049) compared to 152 individuals without depression. Significant positive correlation was found between triglycerides, total cholesterol and LDL-cholesterol concentrations and the BDI-II score (p=0.027, 0.048 and 0.018). Conclusion & Significance: Depressive individuals were found with adverse serum lipid patterns of higher triglycerides and lower HDL-cholesterol levels compared to healthy controls. On this basis, the authors would suggest the implementation of routine serum lipid measurements in order to stratify these patients by their cardiovascular risk.

Hastuti Sri is a Lecturer and Neurologist in Aceh Province, Indonesia. She worked as Faculty of Medicine at Syiah Juala Universit. She completed her Specialist Education at the University of Indonesia. She worked as a Neuropediatric Fellow at University Malaya Medical Center, Kuala Lumpur. She is a Staff of Neurology Department, Zainoel Abidin Hospital, Banda Aceh, Indonesia, Staff of Neuropediatric Division in Neurology Department, Zainoel Abidin Hospital, Banda Aceh Indonesia and Lecturer of Medical Faculty, Syiah Kuala University, Banda Aceh, Indonesia.

Background & Aim: Benign Epilepsy of Childhood with CentralTemporal Spikes (BECTS) is the most common focal epilepsy. It is more common in males and the onset between the ages of 3 and 13 years. Onset of the seizure is during sleep, the incident reaches until 80% of time. The clinical manifestations that mostly appear are secondary generalized seizure with a facial/perioral focal onset. The focal, perioral seizure will be reflected either in the aura or in the form of temporary postictal signs or symptoms. The typical features of this seizure include unilateral paraesthesia of the tongue, lips, gums or cheek; speech arrest, hyper salivation, poor swallowing postictally; involuntary movement of the tongue or jaw; or clonus affecting one side of the face. The feature of EEG is diphasic sharp waves in the central-midtemporal area and usually activated by sleep and unilaterally appears in any given EEG recording. The treatment is required if the seizures are frequent or long and typically respond well to carbamazepine, gabapentine, levetiracetam, sultiame or sodium valproate. Aim is to identify clinical features of signs, symptoms and characteristic of EEG pictures.

Si Nae Kang is medical doctor specialized in Family Medicine, currently has been research fellow in Department of Family Medicine, Seoul National University Hospital, with experience in research, evaluation, teaching . She has special interest in Health promotion and Public health and conducted research on Korean smokers last year. She has developed pilot project of visiting care system for elderly, that is operated successfully now.

While the relationship of leisure time physical activity (LPA) and metabolic syndrome (MetS) is well documented, effectof occupational physical activity (OPA) on MetS is conflicting. Aim of this study is to examine the relationship betweendifferent type of physical activity and risk of metabolic syndrome using a representative sample of South Korean adults. Study included 7057 workers (3795 men and 3262 women) aged 20 to 65 without cancer and arthritis at baseline, from the Korea National Health and Nutrition Examination Survey in 2014-2016. Information on OPA, LPA and commuting physical activity(CPA) were self-reported and blood pressure and biochemical determinations of the blood were also obtained. MetS was defined as the presence of three or more of the National Cholesterol Education Program-Adult Treatment Panel III criteria. Chi-square test and multiple logistic regression analysis were used to investigate relationship between different type of physical activity and MetS. The prevalence of MetS was 25.7 % in the study subject. The percentages of active OPA in MetS and non-MetS groups were 6.7% and 5.0%, respectively. Compared with inactive level of LPA, sufficient level of LPA showed a significantly lower risk of MetS (OR 0.73, 95% CI 0.60-0.89) after adjustment for confounding factors. Conversely, active OPA showed increased risk of MetS (OR 1.09, 95% CI 0.77-1.52), but not reaching statistical significance. CPA was not associated with MetS. LPA showed protective effect of MetS, but OPA showed marginal negative effect on MetS. This difference needs to be considered when recommendations for prevention of MetS are developed.

Gong Deuk Bae is a PhD course student in Gachon university. His research topic is The effect of natural products on the prevention and treatment of type 2 diabetes focusing on pancreatic beta-cells.

Objective: Activation of estrogen receptor signaling plays an important role to preserve functional beta‑cell mass in treatment of diabetes. Liquiritigenin (LQ), a flavonoid isolated from Glycyrrhiza uralensis, is an estrogenic compound which acts as an agonist for the estrogen receptor β. In this study, we investigated protective effect of LQ on palmitate (PA)-induced apoptosis in INS-1 cells.